Click the image above to display a Flash MX applet generated "on the fly", programatically, based on custom data. Click and drag any node. Try overlapping two nodes then click on the one at the back to bring it to the front. Nodes, which represent molecules, are active links. Double-click a node to run a NCBI Protein search on its name. Right-click to zoom in and double-click any small circle to run a DIP protein interaction database search.

Edge (=node connector) ends can have different sizes. Click and drag any node and edge ends will follow, gliding onto the node border. To update edge ends associated with any other node hover the cursor over that node. Notice the node tooltipsColor codes:  plum  = perfect match to database search term;  lavender  = partial match;  ivory  = other interaction partner. Colors can be set to represent gene or protein expression levels.

A molecular interaction cluster containing multiple, smaller clusters. Notice the arrow tip-shaped edge ends. Press the Shift key and click-and-drag in the Flash MX document to select multiple nodes; node colors change to red to mark the selected set. Release the Shift key. Press the Ctrl key and click-and-drag to deselect multiple nodes; node colors revert to original values. Colors can be set/changed both server-side and client-side.

A more complex molecular interaction cluster, with zooming and panning capabilities added to the Flash applet. Use PageUp and PageDown keys to zoom in/out and the Arrow keys to pan left/right and up/down (if your Web browser is not Internet Explorer you may first need to click once in the applet window). Optionally, layout can be more compact. Extremely large cluster interactivity may require adequate hardware for optimal performance.