Dynamic Signaling Maps™ is a powerful Web-based signaling pathway software
suite that allows scientists and biomedical research organizations
to integrate, analyze, manipulate, and visualize biological
signaling pathways and biomolecular interaction data.
Both a productivity and a research tool, Dynamic Signaling
Maps™ significantly improves performance in Life Sciences
Research & Development. It provides decision support in the
development of "cocktail drugs" aimed at multiple molecular targets. In effect,
all blockbuster drugs on the market today control a limited set of
single target molecules. The coordinated, synergic targeting of multiple
molecules will provide the finer level of control required to treat
complex medical conditions such as cardiovascular disease, cancer,
and autoimmune disorders.
Dynamic Signaling Maps™ is seamlessly integrated with Hippron
Interactions Knowledge Base™, a database of
human-curated biomolecular interactions. As a software
tool it helps researchers abstract scientific questions to advanced
levels by dealing with interacting systems of genes, proteins, and
metabolites. It empowers the bench scientist to easily --
- create, store, and update signaling pathways using an
intuitive symbolic language
- do consistency checks when integrating pathway data from
multiple sources
- produce signaling pathway diagrams in a variety of
editable vector graphics formats
- perform signaling event analysis on public and
proprietary pathways
- convert pathway data to a format suitable for database
storage and printing
- integrate pathways with biomolecular interactions from
human curated databases
- display biomolecular interaction clusters as interactive
2D and 3D scalable graphics
- retrieve detailed interaction and molecule data from
linked database records
- extract gene network topologies from time-series
microarray expression profiles
- overlay time-series expression data onto gene network
diagrams
Dynamic Signaling
Maps :: Internet Edition is software-as-a-service that
allows researchers to use Dynamic Signaling Maps™ from
any workstation with Web access, rather than own the software.
Hippron Visualization
Engine™ (HVE) is a Web technology for generating interactive
diagrams of biomolecular interaction clusters and biological
ontologies in Macromedia Flash MX format. Features include: